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A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations

Cell surface antigen discovery is of great interest for biomedical research both for isolation of rare cell populations and therapeutic targeting. We developed a rapid, cost-effective, fully in vitro technology which facilities the simultaneous target discovery and human antibody generation on the s...

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Detalles Bibliográficos
Autores principales: Nixon, Allison M. L., Duque, Alejandro, Yelle, Nicholas, McLaughlin, Megan, Davoudi, Sadegh, Pedley, Nicolas M., Haynes, Jennifer, Brown, Kevin R., Pan, James, Hart, Traver, Gilbert, Penney M., Singh, Sheila K., O’Brien, Catherine A., Sidhu, Sachdev S., Moffat, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351593/
https://www.ncbi.nlm.nih.gov/pubmed/30696911
http://dx.doi.org/10.1038/s41598-018-37462-1