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Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6

Human alpha/beta hydrolase domain 6 (hABHD6) is an enzyme that hydrolyzes 2-arachidonoylglycerol (2-AG), a potent agonist at both cannabinoid CB1 and CB2 receptors. In vivo modulation of ABHD6 expression has been shown to have potential therapeutic applications, making the enzyme a promising drug ta...

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Detalles Bibliográficos
Autores principales: Shields, Christina Miyabe, Zvonok, Nikolai, Zvonok, Alexander, Makriyannis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351631/
https://www.ncbi.nlm.nih.gov/pubmed/30696836
http://dx.doi.org/10.1038/s41598-018-36633-4