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Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients

Immunomodulatory drugs (IMIDs) are very effective in the treatment of multiple myeloma (MM). The description of their cereblon-mediated mechanism of action was a hallmark in MM research. Although the importance of IMID-induced degradation of cereblon-binding proteins is well described in vitro, the...

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Detalles Bibliográficos
Autores principales: Kriegsmann, Katharina, Baertsch, Marc-Andrea, Awwad, Mohamed H. S., Merz, Maximilian, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Becker, Natalia, Benner, Axel, Raab, Marc S., Hillengass, Jens, Bertsch, Uta, Dürig, Jan, Salwender, Hans Jürgen, Hänel, Mathias, Fenk, Roland, Munder, Markus, Weisel, Katja, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Hundemer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351644/
https://www.ncbi.nlm.nih.gov/pubmed/30696815
http://dx.doi.org/10.1038/s41408-019-0174-z