Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo

Benzofuran derivatives have wide range of biological activities as anti-oxidant, anti-inflammatory and anticonvulsant agent. In this study, we investigated whether the novel benzofuran derivative, DK-1014 has the anti-inflammatory effects on macrophage and lung epithelial cells and anti-asthmatic ef...

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Detalles Bibliográficos
Autores principales: Xu, Xuezhen, Kwon, Ok-Kyoung, Shin, In-Sik, Mali, Jyotirling R., Harmalkar, Dipesh S., Lim, Yourim, Lee, Gilhye, Lu, Qili, Oh, Sei-Ryang, Ahn, Kyung-Seop, Jeong, Hye-Gwang, Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351650/
https://www.ncbi.nlm.nih.gov/pubmed/30696844
http://dx.doi.org/10.1038/s41598-018-36925-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351650/
https://www.ncbi.nlm.nih.gov/pubmed/30696844
http://dx.doi.org/10.1038/s41598-018-36925-9

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