Expression of recombinant glutamic acid decarboxylase in insect larvae and its application in an immunoassay for the diagnosis of autoimmune diabetes mellitus

Autoimmune Diabetes Mellitus (DM) is a chronic disease caused by the selective destruction of insulin producing beta cells in human pancreas. DM is characterized by the presence of autoantibodies that bind a variety of islet-cell antigens. The 65 kDa isoform of glutamate decarboxylase (GAD65) is a m...

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Detalles Bibliográficos
Autores principales: Trabucchi, Aldana, Bombicino, Silvina S., Targovnik, Alexandra M., Marfía, Juan I., Sabljic, Adriana V., Faccinetti, Natalia I., Guerra, Luciano L., Iacono, Ruben F., Miranda, María V., Valdez, Silvina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351654/
https://www.ncbi.nlm.nih.gov/pubmed/30696851
http://dx.doi.org/10.1038/s41598-018-35744-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351654/
https://www.ncbi.nlm.nih.gov/pubmed/30696851
http://dx.doi.org/10.1038/s41598-018-35744-2

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