Imaging endogenous macrophage iron deposits reveals a metabolic biomarker of polarized tumor macrophage infiltration and response to CSF1R breast cancer immunotherapy

Iron deposits are a phenotypic trait of tumor-associated macrophages (TAMs). Histological iron imaging and contrast-agent free magnetic resonance imaging (MRI) can detect these deposits, but their presence  in human cancer, and correlation with immunotherapeutic response is largely untested. Here, p...

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Detalles Bibliográficos
Autores principales: Leftin, Avigdor, Ben-Chetrit, Nir, Joyce, Johanna A., Koutcher, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351660/
https://www.ncbi.nlm.nih.gov/pubmed/30696910
http://dx.doi.org/10.1038/s41598-018-37408-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351660/
https://www.ncbi.nlm.nih.gov/pubmed/30696910
http://dx.doi.org/10.1038/s41598-018-37408-7

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