Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method

Several antimalarial drugs are known to prolong ventricular repolarization as evidenced by QT/QTc interval prolongation. This can lead to Torsades de Pointes, a potentially lethal ventricular arrhythmia. Whether this is the case with artemisinin-based combination therapies (ACTs) remains uncertain....

Descripción completa

Detalles Bibliográficos
Autores principales: Funck-Brentano, Christian, Ouologuem, Nouhoum, Duparc, Stephan, Felices, Mathieu, Sirima, Sodiomon B., Sagara, Issaka, Soulama, Issiaka, Ouedraogo, Jean-Bosco, Beavogui, Abdoul H., Borghini-Fuhrer, Isabelle, Khan, Yasmin, Djimdé, Abdoulaye A., Voiriot, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351684/
https://www.ncbi.nlm.nih.gov/pubmed/30696921
http://dx.doi.org/10.1038/s41598-018-37113-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351684/
https://www.ncbi.nlm.nih.gov/pubmed/30696921
http://dx.doi.org/10.1038/s41598-018-37113-5

Ejemplares similares