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Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method

Several antimalarial drugs are known to prolong ventricular repolarization as evidenced by QT/QTc interval prolongation. This can lead to Torsades de Pointes, a potentially lethal ventricular arrhythmia. Whether this is the case with artemisinin-based combination therapies (ACTs) remains uncertain....

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Detalles Bibliográficos
Autores principales:	Funck-Brentano, Christian, Ouologuem, Nouhoum, Duparc, Stephan, Felices, Mathieu, Sirima, Sodiomon B., Sagara, Issaka, Soulama, Issiaka, Ouedraogo, Jean-Bosco, Beavogui, Abdoul H., Borghini-Fuhrer, Isabelle, Khan, Yasmin, Djimdé, Abdoulaye A., Voiriot, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351684/ https://www.ncbi.nlm.nih.gov/pubmed/30696921 http://dx.doi.org/10.1038/s41598-018-37113-5

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