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Cell‐free DNA as a biomarker of aging

Cell‐free DNA (cfDNA) is present in the circulating plasma and other body fluids and is known to originate mainly from apoptotic cells. Here, we provide the first in vivo evidence of global and local chromatin changes in human aging by analyzing cfDNA from the blood of individuals of different age g...

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Detalles Bibliográficos
Autores principales: Teo, Yee Voan, Capri, Miriam, Morsiani, Cristina, Pizza, Grazia, Faria, Ana Maria Caetano, Franceschi, Claudio, Neretti, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351822/
https://www.ncbi.nlm.nih.gov/pubmed/30575273
http://dx.doi.org/10.1111/acel.12890