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Disrupted‐in‐schizophrenia‐1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor

Mitochondrial dysfunction is an early feature of Alzheimer's disease (AD). Accumulated damaged mitochondria, which are associated with impaired mitophagy, contribute to neurodegeneration in AD. We show levels of Disrupted‐in‐schizophrenia‐1 (DISC1), which is genetically associated with psychiat...

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Detalles Bibliográficos
Autores principales: Wang, Zhao‐Tao, Lu, Mei‐Hong, Zhang, Yan, Ji, Wen‐Li, Lei, Lei, Wang, Wang, Fang, Li‐Pao, Wang, Lu‐Wen, Yu, Fan, Wang, Ji, Li, Zhen‐Yu, Wang, Jian‐Rong, Wang, Ting‐Hua, Dou, Fei, Wang, Qin‐Wen, Wang, Xing‐Long, Li, Shao, Ma, Quan‐Hong, Xu, Ru‐Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351828/
https://www.ncbi.nlm.nih.gov/pubmed/30488644
http://dx.doi.org/10.1111/acel.12860