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Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet

Hutchinson‐Gilford Progeria Syndrome (HGPS) is a devastating premature aging disease. Mouse models have been instrumental for understanding HGPS mechanisms and for testing therapies, which to date have had only marginal benefits in mice and patients. Barriers to developing effective therapies includ...

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Detalles Bibliográficos
Autores principales: Kreienkamp, Ray, Billon, Cyrielle, Bedia‐Diaz, Gonzalo, Albert, Carolyn J., Toth, Zacharie, Butler, Andrew A., McBride‐Gagyi, Sara, Ford, David A., Baldan, Angel, Burris, Thomas P., Gonzalo, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351834/
https://www.ncbi.nlm.nih.gov/pubmed/30548460
http://dx.doi.org/10.1111/acel.12852