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Senescent cells: A new Achilles’ heel to exploit for cancer medicine?

Cellular senescence is a typical tumor‐suppressive mechanism that restricts the proliferation of premalignant cells. However, mounting evidence suggests that senescent cells, which also persist in vivo, can promote the incidence of aging‐related disorders principally via the senescence‐associated se...

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Detalles Bibliográficos
Autores principales: Zhang, Boyi, Lam, Eric W.‐F., Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351840/
https://www.ncbi.nlm.nih.gov/pubmed/30450821
http://dx.doi.org/10.1111/acel.12875