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Amyloid β‐induced elevation of O‐GlcNAcylated c‐Fos promotes neuronal cell death

Alzheimer's disease (AD) is an age‐related neurodegenerative disease characterized by progressive memory loss resulting from cumulative neuronal cell death. O‐linked β‐N‐acetyl glucosamine (O‐GlcNAc) modification of the proteins reflecting glucose metabolism is altered in the brains of patients...

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Detalles Bibliográficos
Autores principales: Choi, Heesun, Kim, Chaeyoung, Song, Hyundong, Cha, Moon‐Yong, Cho, Hyun Jin, Son, Sung Min, Kim, Haeng Jun, Mook‐Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351842/
https://www.ncbi.nlm.nih.gov/pubmed/30515991
http://dx.doi.org/10.1111/acel.12872