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Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis

The insulin‐IGF‐1/DAF‐2 pathway has a central role in the determination of aging and longevity in Caenorhabditis elegans and other organisms. In this paper, we measured neuronal insulin secretion (using INS‐22::Venus) during C. elegans lifespan and monitored how this secretion is modified by redox h...

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Detalles Bibliográficos
Autores principales: Minniti, Alicia N., Arriagada, Héctor, Zúñiga, Soledad, Bravo‐Zehnder, Marcela, Alfaro, Iván E., Aldunate, Rebeca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846/
https://www.ncbi.nlm.nih.gov/pubmed/30456853
http://dx.doi.org/10.1111/acel.12855