Drosophila insulin‐like peptide dilp1 increases lifespan and glucagon‐like Akh expression epistatic to dilp2

Insulin/IGF signaling (IIS) regulates essential processes including development, metabolism, and aging. The Drosophila genome encodes eight insulin/IGF‐like peptide (dilp) paralogs, including tandem‐encoded dilp1 and dilp2. Many reports show that longevity is increased by manipulations that decrease...

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Detalles Bibliográficos
Autores principales: Post, Stephanie, Liao, Sifang, Yamamoto, Rochele, Veenstra, Jan A., Nässel, Dick R., Tatar, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351851/
https://www.ncbi.nlm.nih.gov/pubmed/30511458
http://dx.doi.org/10.1111/acel.12863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351851/
https://www.ncbi.nlm.nih.gov/pubmed/30511458
http://dx.doi.org/10.1111/acel.12863

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