Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Metazoans viability depends on their ability to regulate metabolic processes and also to respond to harmful challenges by mounting anti‐stress responses; these adaptations were fundamental forces during evolution. Central to anti‐stress responses are a number of short‐lived transcription factors tha...

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Detalles Bibliográficos
Autores principales: Tsakiri, Eleni N., Gumeni, Sentiljana, Iliaki, Kalliopi K., Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos P., Gorgoulis, Vassilis G., Mikros, Emmanuel, Scorrano, Luca, Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351879/
https://www.ncbi.nlm.nih.gov/pubmed/30537423
http://dx.doi.org/10.1111/acel.12845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351879/
https://www.ncbi.nlm.nih.gov/pubmed/30537423
http://dx.doi.org/10.1111/acel.12845

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