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Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation
Metazoans viability depends on their ability to regulate metabolic processes and also to respond to harmful challenges by mounting anti‐stress responses; these adaptations were fundamental forces during evolution. Central to anti‐stress responses are a number of short‐lived transcription factors tha...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351879/ https://www.ncbi.nlm.nih.gov/pubmed/30537423 http://dx.doi.org/10.1111/acel.12845 |