Pirfenidone, an Anti-Fibrotic Drug, Suppresses the Growth of Human Prostate Cancer Cells by Inducing G(1) Cell Cycle Arrest

Pirfenidone (PFD) is an anti-fibrotic drug used to treat idiopathic pulmonary fibrosis by inducing G(1) cell cycle arrest in fibroblasts. We hypothesize that PFD can induce G(1) cell cycle arrest in different types of cells, including cancer cells. To investigate the effects of PFD treatment on the...

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Detalles Bibliográficos
Autores principales: Ishii, Kenichiro, Sasaki, Takeshi, Iguchi, Kazuhiro, Kato, Manabu, Kanda, Hideki, Hirokawa, Yoshifumi, Arima, Kiminobu, Watanabe, Masatoshi, Sugimura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351920/
https://www.ncbi.nlm.nih.gov/pubmed/30621175
http://dx.doi.org/10.3390/jcm8010044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351920/
https://www.ncbi.nlm.nih.gov/pubmed/30621175
http://dx.doi.org/10.3390/jcm8010044

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