Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study

N’-nitrosonornicotine (NNN) is one of the tobacco-specific nitrosamines (TSNAs) that exists widely in smoke and smokeless tobacco products. NNN can induce tumors in various laboratory animal models and has been identified by International Agency for Research on Cancer (IARC) as a human carcinogen. M...

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Detalles Bibliográficos
Autores principales: Fan, Tengjiao, Sun, Guohui, Zhao, Lijiao, Cui, Xin, Zhong, Rugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352179/
https://www.ncbi.nlm.nih.gov/pubmed/30634532
http://dx.doi.org/10.3390/ijerph16020178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352179/
https://www.ncbi.nlm.nih.gov/pubmed/30634532
http://dx.doi.org/10.3390/ijerph16020178

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