Cargando…

Amyloid β perturbs elevated heme flux induced with neuronal development

INTRODUCTION: Heme is a central molecule in mitochondrial respiration and ATP generation in neuronal cells. Thus, we assessed the importance of altered heme metabolism in Alzheimer's disease (AD) pathogenesis. METHODS: To investigate the role of altered heme metabolism in AD, we identified heme...

Descripción completa

Detalles Bibliográficos
Autores principales: Vidal, Chantal, Daescu, Kelly, Fitzgerald, Keely E., Starokadomska, Anna, Bezprozvanny, Ilya, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352316/
https://www.ncbi.nlm.nih.gov/pubmed/30723777
http://dx.doi.org/10.1016/j.trci.2018.12.003