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Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs

BACKGROUND: Autophagy has emerged as a key mechanism in the survival and function of T and B lymphocytes, and its activation was involved in apoptosis resistance in rheumatoid arthritis (RA). To investigate whether the relationship between autophagy and apoptosis may impact the response to the thera...

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Detalles Bibliográficos
Autores principales: Vomero, M., Manganelli, V., Barbati, C., Colasanti, T., Capozzi, A., Finucci, A., Spinelli, F. R., Ceccarelli, F., Perricone, C., Truglia, S., Morrone, S., Maggio, R., Misasi, R., Bombardieri, M., Di Franco, M., Conti, F., Sorice, M., Valesini, G., Alessandri, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352385/
https://www.ncbi.nlm.nih.gov/pubmed/30696478
http://dx.doi.org/10.1186/s13075-019-1818-x