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Neuroprotective effects of human bone marrow mesenchymal stem cells against cerebral ischemia are mediated in part by an anti-apoptotic mechanism

Transplantation of human bone marrow mesenchymal stem cells (hMSCs) stands as a potent stroke therapy, but its exact mechanism remains unknown. This study investigated the anti-apoptotic mechanisms by which hMSCs exert neuroprotective effects on cerebral ischemia. Primary mixed cultures of rat neuro...

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Detalles Bibliográficos
Autores principales: Zhang, Yuyang, Yu, Seongjin, Tuazon, Julian P., Lee, Jea-Young, Corey, Sydney, Kvederis, Lauren, Kingsbury, Chase, Kaneko, Yuji, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352592/
https://www.ncbi.nlm.nih.gov/pubmed/30632499
http://dx.doi.org/10.4103/1673-5374.247464