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Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism

A hepatic comorbidity of metabolic syndrome, known as nonalcoholic fatty liver disease (NAFLD), is increasing in prevalence in conjunction with the pandemics of obesity and diabetes. The spectrum of NAFLD ranges from simple hepatic fat accumulation to a more severe disease termed nonalcoholic steato...

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Detalles Bibliográficos
Autores principales: McCommis, Kyle S., Finck, Brian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352854/
https://www.ncbi.nlm.nih.gov/pubmed/30686780
http://dx.doi.org/10.1016/j.jcmgh.2018.09.017