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Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

Background: Stressful life events (SLEs) and neuroticism are risk factors for major depressive disorder (MDD). However, SLEs and neuroticism are heritable and genetic risk for SLEs is associated with risk for MDD. We sought to investigate the genetic and environmental contributions to SLEs in a fami...

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Detalles Bibliográficos
Autores principales: Clarke, Toni-Kim, Zeng, Yanni, Navrady, Lauren, Xia, Charley, Haley, Chris, Campbell, Archie, Navarro, Pau, Amador, Carmen, Adams, Mark J., Howard, David M., Soler, Aleix, Hayward, Caroline, Thomson, Pippa A., Smith, Blair H., Padmanabhan, Sandosh, Hocking, Lynne J., Hall, Lynsey S., Porteous, David J., Deary, Ian J., McIntosh, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352921/
https://www.ncbi.nlm.nih.gov/pubmed/30756089
http://dx.doi.org/10.12688/wellcomeopenres.13893.2