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The dynamic side of the Warburg effect: glycolytic intermediate storage as buffer for fluctuating glucose and O (2) supply in tumor cells

Background: Tumor cells often show altered metabolism which supports uncontrolled proliferation. A classic example is the Warburg effect: high glucose uptake and lactate production despite sufficient oxygen supply. Remarkably, tumor cells can transiently take up glucose even an order of magnitude fa...

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Detalles Bibliográficos
Autor principal: van Beek, Johannes H.G.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352925/
https://www.ncbi.nlm.nih.gov/pubmed/30755789
http://dx.doi.org/10.12688/f1000research.15635.2