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An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer

Tumour hypoxia contributes to poor treatment outcome in locally advanced rectal cancer (LARC) and circulating extracellular vesicles (EVs) as potential biomarkers of tumour hypoxia and adverse prognosis have not been fully explored. We examined EV miRNAs from hypoxic colorectal cancer cell lines as...

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Detalles Bibliográficos
Autores principales: Bjørnetrø, Tonje, Redalen, Kathrine Røe, Meltzer, Sebastian, Thusyanthan, Nirujah Sivarajah, Samiappan, Rampradeep, Jegerschöld, Caroline, Handeland, Karianne Risberg, Ree, Anne Hansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352936/
https://www.ncbi.nlm.nih.gov/pubmed/30728923
http://dx.doi.org/10.1080/20013078.2019.1567219