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Alterations of DNA Methylation at GDNF Gene Promoter in the Ventral Tegmental Area of Adult Depression-Like Rats Induced by Maternal Deprivation

Objective: To study the expression and DNA methylation of the Glial cell line-derived neurotrophic factor (GDNF) gene in the development of depression-like behaviors in rats experiencing maternal deprivation stress in early life. Methods: Newborn SD rats were randomly assigned to a normal control gr...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Wang, Lei, Wang, Xin, Wang, Yuting, Li, Chuting, Zhu, Xiongzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353043/
https://www.ncbi.nlm.nih.gov/pubmed/30728784
http://dx.doi.org/10.3389/fpsyt.2018.00732