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Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms

BACKGROUND: The human filarial parasite Onchocerca volvulus is the causative agent of onchocerciasis (river blindness). It causes blindness in 270,000 individuals with an additional 6.5 million suffering from severe skin pathologies. Current international control programs focus on the reduction of m...

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Detalles Bibliográficos
Autores principales: Voronin, Denis, Tricoche, Nancy, Jawahar, Shabnam, Shlossman, Michael, Bulman, Christina A., Fischer, Chelsea, Suderman, Michael T., Sakanari, Judy A., Lustigman, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353222/
https://www.ncbi.nlm.nih.gov/pubmed/30653499
http://dx.doi.org/10.1371/journal.pntd.0007108