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Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a rare bone tumor with a high propensity for lung metastasis and poor patient outcomes. It is crucial to identify novel therapeutic strategies and biomarkers. PATIENTS AND METHODS: ARK1C1 staining was detected in OS specimens, and its clinical significance was assess...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Liu, Yang, Yu, Guanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353227/
https://www.ncbi.nlm.nih.gov/pubmed/30774369
http://dx.doi.org/10.2147/OTT.S165647