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Cell of Origin and Cancer Stem Cells in Tumor Suppressor Mouse Models of Glioblastoma

The cellular origins and the mechanisms of progression, maintenance of tumorigenicity, and therapeutic resistance are central questions in the glioblastoma multiforme (GBM) field. Using tumor suppressor mouse models, our group recently reported two independent populations of adult GBM-initiating cen...

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Detalles Bibliográficos
Autores principales: Alcantara Llaguno, Sheila R., Xie, Xuanhua, Parada, Luis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353557/
https://www.ncbi.nlm.nih.gov/pubmed/27815542
http://dx.doi.org/10.1101/sqb.2016.81.030973