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Equilin in conjugated equine estrogen increases monocyte-endothelial adhesion via NF-κB signaling

The adhesion of monocytes to endothelial cells, which is mediated by adhesion molecules, plays a crucial role in the onset of atherosclerosis. Conjugated equine estrogen, which is widely used for estrogen-replacement therapy, contains both estrone sulfate and various nonhuman estrogens, including eq...

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Detalles Bibliográficos
Autores principales: Ito, Fumitake, Mori, Taisuke, Tarumi, Yosuke, Okimura, Hiroyuki, Kataoka, Hisashi, Tanaka, Yukiko, Koshiba, Akemi, Kitawaki, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353580/
https://www.ncbi.nlm.nih.gov/pubmed/30699196
http://dx.doi.org/10.1371/journal.pone.0211462