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Personalization of Logical Models With Multi-Omics Data Allows Clinical Stratification of Patients
Logical models of cancer pathways are typically built by mining the literature for relevant experimental observations. They are usually generic as they apply for large cohorts of individuals. As a consequence, they generally do not capture the heterogeneity of patient tumors and their therapeutic re...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353844/ https://www.ncbi.nlm.nih.gov/pubmed/30733688 http://dx.doi.org/10.3389/fphys.2018.01965 |