Impact of APOL1 Genetic Variants on HIV-1 Infection and Disease Progression

Apolipoprotein L1 (APOL1) has broad innate immune functions and has been shown to restrict HIV replication in vitro by multiple mechanisms. Coding variants in APOL1 are strongly associated with HIV-associated nephropathy (HIVAN) in persons with untreated HIV infection; however, the mechanism by whic...

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Detalles Bibliográficos
Autores principales: An, Ping, Kirk, Gregory D., Limou, Sophie, Binns-Roemer, Elizabeth, Kopp, Jeffrey B., Winkler, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353846/
https://www.ncbi.nlm.nih.gov/pubmed/30733721
http://dx.doi.org/10.3389/fimmu.2019.00053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353846/
https://www.ncbi.nlm.nih.gov/pubmed/30733721
http://dx.doi.org/10.3389/fimmu.2019.00053

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