Methylation in MIRLET7A3 Gene Induces the Expression of IGF-II and Its mRNA Binding Proteins IGF2BP-2 and 3 in Hepatocellular Carcinoma

miR-let-7a is a tumor suppressor miRNA with reduced expression in most cancers. Methylation of MIRLET7A3 gene was reported to be the cause of this suppression in several cancers; however, it was not explicitly investigated in hepatocellular carcinoma (HCC). We aimed at investigating miR-let-7a expre...

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Detalles Bibliográficos
Autores principales: Waly, Amr A., El-Ekiaby, Nada, Assal, Reem A., Abdelrahman, Mohamed M., Hosny, Karim A., El Tayebi, Hend M., Esmat, Gamal, Breuhahn, Kai, Abdelaziz, Ahmed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353855/
https://www.ncbi.nlm.nih.gov/pubmed/30733684
http://dx.doi.org/10.3389/fphys.2018.01918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353855/
https://www.ncbi.nlm.nih.gov/pubmed/30733684
http://dx.doi.org/10.3389/fphys.2018.01918

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