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Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection

The exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal immunity gene, mucin-13 (MUC13), is strongly upregulated during Plasmodium...

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Detalles Bibliográficos
Autores principales: LaMonte, Gregory M., Orjuela-Sanchez, Pamela, Calla, Jaeson, Wang, Lawrence T., Li, Shangzhong, Swann, Justine, Cowell, Annie N., Zou, Bing Yu, Abdel-Haleem Mohamed, Alyaa M., Villa Galarce, Zaira Hellen, Moreno, Marta, Tong Rios, Carlos, Vinetz, Joseph M., Lewis, Nathan, Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353872/
https://www.ncbi.nlm.nih.gov/pubmed/30700707
http://dx.doi.org/10.1038/s41467-019-08349-0