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Dynamic metrics-based biomarkers to predict responders to anti-PD-1 immunotherapy
BACKGROUND: Anti-PD-1 immunotherapies have shown clinical benefit in multiple cancers, but response was only observed in a subset of patients. Predicting which patients will respond is an urgent clinical need, but current companion diagnosis based on PD-L1 IHC staining shows limited predictability....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353899/ https://www.ncbi.nlm.nih.gov/pubmed/30587849 http://dx.doi.org/10.1038/s41416-018-0363-8 |