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Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts

Osteoclasts (OCs) are bone-resorbing cells that originate from hematopoietic stem cells and develop through the fusion of mononuclear myeloid precursors. Dysregulation of OC development causes bone disorders such as osteopetrosis, osteoporosis, and rheumatoid arthritis. Although the molecular mechan...

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Detalles Bibliográficos
Autores principales: Bae, Sung-Jin, Shin, Min Wook, Son, Taekwon, Lee, Hye Shin, Chae, Ji Soo, Jeon, Sejin, Oh, Goo Taeg, Kim, Kyu-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353902/
https://www.ncbi.nlm.nih.gov/pubmed/30700695
http://dx.doi.org/10.1038/s12276-018-0201-3