Age-related differences in the bone marrow stem cell niche generate specialized microenvironments for the distinct regulation of normal hematopoietic and leukemia stem cells

The bone marrow (BM) microenvironment serves as a stem cell niche regulating the in vivo cell fate of normal hematopoietic stem cells (HSC) as well as leukemia stem cells (LSCs). Accumulating studies have indicated that the regeneration of normal HSCs and the process of leukemogenesis change with ad...

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Detalles Bibliográficos
Autores principales: Lee, Ga-Young, Jeong, Seon-Yeong, Lee, Hae-Ri, Oh, Il-Hoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353913/
https://www.ncbi.nlm.nih.gov/pubmed/30700727
http://dx.doi.org/10.1038/s41598-018-36999-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353913/
https://www.ncbi.nlm.nih.gov/pubmed/30700727
http://dx.doi.org/10.1038/s41598-018-36999-5

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