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Differentiating between cancer and normal tissue samples using multi-hit combinations of genetic mutations

Cancer is known to result from a combination of a small number of genetic defects. However, the specific combinations of mutations responsible for the vast majority of cancers have not been identified. Current computational approaches focus on identifying driver genes and mutations. Although individ...

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Detalles Bibliográficos
Autores principales: Dash, Sajal, Kinney, Nicholas A., Varghese, Robin T., Garner, Harold R., Feng, Wu-chun, Anandakrishnan, Ramu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353925/
https://www.ncbi.nlm.nih.gov/pubmed/30700767
http://dx.doi.org/10.1038/s41598-018-37835-6