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Differentiating between cancer and normal tissue samples using multi-hit combinations of genetic mutations
Cancer is known to result from a combination of a small number of genetic defects. However, the specific combinations of mutations responsible for the vast majority of cancers have not been identified. Current computational approaches focus on identifying driver genes and mutations. Although individ...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353925/ https://www.ncbi.nlm.nih.gov/pubmed/30700767 http://dx.doi.org/10.1038/s41598-018-37835-6 |