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Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells
Solid stress is a biomechanical abnormality of the tumor microenvironment that plays a crucial role in tumor progression. When it is applied to cancer cells, solid stress hinders their proliferation rate and promotes cancer cell invasion and metastatic potential. However, the underlying mechanisms o...
Autores principales: | Kalli, Maria, Minia, Angeliki, Pliaka, Vaia, Fotis, Christos, Alexopoulos, Leonidas G., Stylianopoulos, Triantafyllos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353927/ https://www.ncbi.nlm.nih.gov/pubmed/30700740 http://dx.doi.org/10.1038/s41598-018-37425-6 |
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