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Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening

Fibrous scaffolds are used for bone tissue engineering purposes with great success across a variety of polymers with different physical and chemical properties. It is now evident that the correct degree of curvature promotes increased cytoskeletal tension on osteoprogenitors leading to osteogenic di...

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Detalles Bibliográficos
Autores principales: Ozdemir, Tugba, Bowers, Daniel T., Zhan, Xiang, Ghosh, Debashis, Brown, Justin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353928/
https://www.ncbi.nlm.nih.gov/pubmed/30700820
http://dx.doi.org/10.1038/s41598-018-37554-y