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Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening
Fibrous scaffolds are used for bone tissue engineering purposes with great success across a variety of polymers with different physical and chemical properties. It is now evident that the correct degree of curvature promotes increased cytoskeletal tension on osteoprogenitors leading to osteogenic di...
Autores principales: | Ozdemir, Tugba, Bowers, Daniel T., Zhan, Xiang, Ghosh, Debashis, Brown, Justin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353928/ https://www.ncbi.nlm.nih.gov/pubmed/30700820 http://dx.doi.org/10.1038/s41598-018-37554-y |
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