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A high-throughput integrated microfluidics method enables tyrosine autophosphorylation discovery

Autophosphorylation of receptor and non-receptor tyrosine kinases is a common molecular switch with broad implications for pathogeneses and therapy of cancer and other human diseases. Technologies for large-scale discovery and analysis of autophosphorylation are limited by the inherent difficulty to...

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Detalles Bibliográficos
Autores principales: Nevenzal, Hadas, Noach-Hirsh, Meirav, Skornik-Bustan, Or, Brio, Lev, Barbiro-Michaely, Efrat, Glick, Yair, Avrahami, Dorit, Lahmi, Roxane, Tzur, Amit, Gerber, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353932/
https://www.ncbi.nlm.nih.gov/pubmed/30729180
http://dx.doi.org/10.1038/s42003-019-0286-9