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Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease

Obesity-induced adipose-tissue dysfunction is a critical contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). B cell-activating factor (BAFF) is an adipokine related to impaired insulin sensitivity, and the serum BAFF concentration is associated with NAFLD severity. In this s...

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Detalles Bibliográficos
Autores principales: Nakamura, Yoshiko, Abe, Masanori, Kawasaki, Keitarou, Miyake, Teruki, Watanabe, Takao, Yoshida, Osamu, Hirooka, Masashi, Matsuura, Bunzo, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353938/
https://www.ncbi.nlm.nih.gov/pubmed/30700810
http://dx.doi.org/10.1038/s41598-018-37403-y