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Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates

Membraneless compartments, such as complex coacervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their compatibility with essential RNA World chemistries is unclear. We show that such compartments can enhance key prebiotically-r...

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Detalles Bibliográficos
Autores principales: Poudyal, Raghav R., Guth-Metzler, Rebecca M., Veenis, Andrew J., Frankel, Erica A., Keating, Christine D., Bevilacqua, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353945/
https://www.ncbi.nlm.nih.gov/pubmed/30700721
http://dx.doi.org/10.1038/s41467-019-08353-4