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RNA-Seq transcriptome analysis shows anti-tumor actions of melatonin in a breast cancer xenograft model

Melatonin is a pleiotropic anti-cancer molecule that controls cancer growth by multiple mechanisms. RNA-Seq can potentially evaluate therapeutic response and its use in xenograft tumor models can differentiate the changes that occur specifically in tumor cells or in the tumor microenvironment (TME)....

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Detalles Bibliográficos
Autores principales: Jardim-Perassi, Bruna Victorasso, Alexandre, Pâmela A., Sonehara, Nathalia M., de Paula-Junior, Rubens, Reis Júnior, Osvaldo, Fukumasu, Heidge, Chammas, Roger, Coutinho, Luiz Lehmann, Zuccari, Debora Aparecida Pires de Campos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353949/
https://www.ncbi.nlm.nih.gov/pubmed/30700756
http://dx.doi.org/10.1038/s41598-018-37413-w