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RNA-Seq transcriptome analysis shows anti-tumor actions of melatonin in a breast cancer xenograft model
Melatonin is a pleiotropic anti-cancer molecule that controls cancer growth by multiple mechanisms. RNA-Seq can potentially evaluate therapeutic response and its use in xenograft tumor models can differentiate the changes that occur specifically in tumor cells or in the tumor microenvironment (TME)....
Autores principales: | Jardim-Perassi, Bruna Victorasso, Alexandre, Pâmela A., Sonehara, Nathalia M., de Paula-Junior, Rubens, Reis Júnior, Osvaldo, Fukumasu, Heidge, Chammas, Roger, Coutinho, Luiz Lehmann, Zuccari, Debora Aparecida Pires de Campos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353949/ https://www.ncbi.nlm.nih.gov/pubmed/30700756 http://dx.doi.org/10.1038/s41598-018-37413-w |
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