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Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma

BACKGROUND: An immunosuppressive microenvironment is critical for cancer initiation and progression. Whether interferon alpha (IFNα) can suppress immune and cancer cells and its involved mechanism still remain largely elusive. METHODS: We examine the expression of interferon alpha/beta receptor-1 (I...

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Detalles Bibliográficos
Autores principales: Ma, Hailong, Yang, Wenyi, Zhang, Liming, Liu, Shuli, Zhao, Mei, Zhou, Ge, Wang, Lizhen, Jin, Shufang, Zhang, Zhiyuan, Hu, Jingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353953/
https://www.ncbi.nlm.nih.gov/pubmed/30555157
http://dx.doi.org/10.1038/s41416-018-0352-y