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Mitotic chromosome binding predicts transcription factor properties in interphase

Mammalian transcription factors (TFs) differ broadly in their nuclear mobility and sequence-specific/non-specific DNA binding. How these properties affect their ability to occupy specific genomic sites and modify the epigenetic landscape is unclear. The association of TFs with mitotic chromosomes ob...

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Detalles Bibliográficos
Autores principales: Raccaud, Mahé, Friman, Elias T., Alber, Andrea B., Agarwal, Harsha, Deluz, Cédric, Kuhn, Timo, Gebhardt, J. Christof M., Suter, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353955/
https://www.ncbi.nlm.nih.gov/pubmed/30700703
http://dx.doi.org/10.1038/s41467-019-08417-5